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April 2025 Medicare Drug List Updates: Twenty-eight (28) medications added to the 2025 Medicare Part D Drug plan formularies.

Category: Monthly Formulary changes
Published: Apr 26, 2025 01:27:54
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The April 2025 Medicare Part D prescription drug plan formulary (drug list) data is now online and included in our Formulary Browser and Q1Rx Drug Finder.

The April formulary updates include the addition of 43 new National Drug Codes (NDCs), representing 28 different prescription drugs, many with multiple strengths.

The formulary updates impact both stand-alone Medicare Part D plans (PDPs) and Medicare Advantage plans with drug coverage (MAPDs).
Please note that these generic and brand-name drugs may not be available on all Medicare Part D and Medicare Advantage drug plans - and you can review the chart below to see the (often limited) number of plan formularies that include these drugs.


Reminders about Medicare prescription drug plan formulary changes
  1. Medicare Part D plans (PDPs and MAPDs) can change their formulary or drug list during the year and may drop one of your formulary medication mid-year for specific Medicare-allowable reasons (such as a new generic drug is available), but there are steps you can take if your medication is no longer covered by your prescription drug plan.

  2. In most cases, your Medicare Part D plan will notify you if the plan drops a medication you are currently using.

Good to know: What is the NDC?

The NDC or National Drug Code is used to uniquely identify a particular drug, manufacturer, strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the drug manufacturer, the second set of number identifies the product and strength, and the third set of numbers identifies the packaging.  You can read more here: Q1FAQ.com/155


Summary of April 2025 NDC changes

There are many reasons for NDCs to be added to the Medicare Part D program, a summary for all 43 new April 2025 NDCs is as follows:

Reason for NDC Addition Occurrences
New Delivery Form and Strength5
New Drug10
New Drug and Delivery Form2
New Drug and Strength12
New Drug, Delivery Form and Strength3
New Manufacturer and Delivery Form1
New Manufacturer and Strength4
New Strength6
Grand Total43

The following chart details the 43 new manufacturer / drug-strength / packaging combinations (NDCs) that were added to one or more Medicare Part D formularies in the most recent updates -- as you will notices, some drugs are only covered by a few Medicare plans.

You can click on the Drug Name below to go to our Q1Medicare.com Drug Finder (Q1Rx.com) and see the details of how this drug is covered by all Medicare Part D plans (PDPs) in Florida (our example state).  You can then change the state in our search form for details of drug coverage in your service area.


NDC Drug Name Number of
PDP Formularies*		 Number of
MAPD Formularies*		 Notes
61314032520 ADALIMUMAB-ADAZ(CF) PEN 80 MG PEN INJECTOR [Hyrimoz] 3 17 New Strength
51167012101 ALYFTREK 10-50-125 MG TABLET 6 126 New Drug and Strength
51167013501 ALYFTREK 4-20-50 MG TABLET 6 126 New Drug and Strength
50474078284 BIMZELX 320 MG/2 ML AUTOINJECTOR 0 6 New Strength
50474078378 BIMZELX 320 MG/2 ML SYRINGE 0 6 New Strength
51672405001 CARBAMAZEPINE 200 MG CHEWABLE TABLET 19 205 New Delivery Form and Strength
00406895401 DEXTROAMP-AMPHET ER 20 MG CAPSULE 24H [Adderall XR] 37 334 New Manufacturer and Strength
74157001390 GABARONE 100 MG TABLET 0 7 New Drug and Strength
74157011190 GABARONE 400 MG TABLET 0 7 New Drug and Strength
61958180301 HARVONI 45-200 MG TABLET 8 145 New Strength
00781354525 HEPARIN SOD 5,000 UNIT/ML VIAL 40 344 New Strength
73352045501 HYDROCORTISONE 2.5% SOLUTION [Texacort] 0 2 New Drug
82667040003 ILEVRO 0.3% OPHTH EYE DROPS w/DROPPER 14 151 New Drug
83257001411 INSULIN GLARGINE-YFGN U100 VIAL [Semglee] 0 17 New Manufacturer and Delivery Form
66993010006 LEVETIRACETAM 250 MG TABLET SUSP [Spritam] 10 182 New Drug
50742035401 MESNA 400 MG TABLET [Mesnex] 40 334 New Drug
64980057201 METHYLDOPA 500 MG TABLET [Aldomet] 8 51 New Drug
70748032214 MINZOYA-28 TABLET [Joyeaux] 6 19 New Drug
16729027310 PRASUGREL 10 MG TABLET [Effient] 36 338 New Manufacturer and Strength
00006508501 PREVYMIS 120 MG PELLET PACK 15 135 New Delivery Form and Strength
00006508601 PREVYMIS 20 MG PELLET PACK 15 101 New Delivery Form and Strength
00006351659 PRIMAXIN 500 MG VIAL 0 8 New Drug
70954059610 PRUCALOPRIDE 1 MG TABLET [Motegrity] 1 19 New Drug and Strength
70954059710 PRUCALOPRIDE 2 MG TABLET [Motegrity] 1 19 New Drug and Strength
66758027401 RITALIN 10 MG TABLET 0 4 New Manufacturer and Strength
66758027501 RITALIN 20 MG TABLET 0 4 New Manufacturer and Strength
83257001233 SEMGLEE (YFGN) 100 UNIT/ML INSULIN PEN 0 60 New Drug and Delivery Form
83257001111 SEMGLEE (YFGN) 100 UNIT/ML VIAL 0 60 New Drug and Delivery Form
51759038622 SIMLANDI(CF) 20 MG/0.2 ML SYRINGE KIT 18 83 New Delivery Form and Strength
51759052321 SIMLANDI(CF) 80 MG/0.8 ML SYRINGE KIT 18 83 New Delivery Form and Strength
00069025230 TALZENNA 0.1 MG SOFTGEL CAPSULE 40 344 New Drug and Strength
00069035330 TALZENNA 0.25 MG SOFTGEL CAPSULE 40 344 New Drug and Strength
00069045430 TALZENNA 0.35 MG SOFTGEL CAPSULE 40 344 New Drug and Strength
00069054630 TALZENNA 0.5 MG SOFTGEL CAPSULE 40 344 New Drug and Strength
00069065530 TALZENNA 0.75 MG SOFTGEL CAPSULE 40 344 New Drug and Strength
00069075730 TALZENNA 1 MG SOFTGEL CAPSULE 40 344 New Drug and Strength
70069069601 TIMOLOL 0.5% EYE DROPS [Betimol] 1 86 New Drug
68382049814 TOPIRAMATE 50 MG SPRINKLE CAPSULE 20 216 New Strength
10370026801 TRETINOIN 10 MG CAPSULE [Vesanoid] 40 344 New Drug
71860010101 TRYNGOLZA 80 MG/0.8 ML AUTO INJECTOR 0 5 New Drug
84612087601 WEZLANA 45 MG/0.5 ML SYRINGE 1 22 New Drug, Delivery Form and Strength
84612085501 WEZLANA 45 MG/0.5 ML VIAL 1 22 New Drug, Delivery Form and Strength
84612088901 WEZLANA 90 MG/ML SYRINGE 1 22 New Drug, Delivery Form and Strength




If your brand-name drug is no longer covered by your Medicare Part D plan, you can use the 30-day notice period (if notice is provided) to:
Learn more in our article: How a mid-year formulary change can affect your Medicare Part D drug coverage.

Our online Formulary Browser and Drug Finder

You can review any Medicare plan formulary using the Q1Medicare.com Formulary Browser found at: FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your Service Area using our Drug Finder found at: Q1Rx.com.

Additional Formulary Drug Change Articles:

Medicare Part D Plan Formulary (Drug Lists) Updates:
April 2025, March 2025, June 2024, May 2024, April 2024, September 2023, August 2023, June 2023, May 2023, April 2023, March 2023, February 2023, August 2022, June 2022, May 2022, April 2022, March 2022, February 2022, August 2021, June 2021, May 2021, April 2021, September 2020, August 2020, June 2020, May 2020, April 2020, March 2020, September 2019, July 2019, June 2019, May 2019, April 2019, March 2019, August 2018, July 2018, June 2018, May 2018, April 2018, August 2017, July 2017, May 2017, April 2017, August 2016, July 2016, June 2016, April 2016, March 2016, October 2015, August 2015, July 2015, May 2015, April 2015, August 2014, May 2014, August 2013, June 2013, May 2013, April 2013, August 2012, July 2012, June 2012

Formulary Changes to the Top Medicare Drugs:
April 2025, June 2024, September 2023, September 2022, September 2021, September 2020, April 2020, September 2019, April 2019, August 2018, April 2018, August 2017, April 2017, August 2016, April 2016, October 2015, April 2015, August 2014, August 2013, April 2013

New Generic Equivalents Added to Formularies:
May 2024, June 2023, February 2023, August 2021, June 2021, May 2021, April 2021, September 2020, August 2020, June 2020, May 2020, April 2020, March 2020, September 2019, July 2019, June 2019, May 2019, April 2019, March 2019, August 2018, July 2018, April 2018, August 2017, July 2017, April 2017, March & April 2016, April & May 2015, August 2014, May 2014


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