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March 2025 Medicare Drug List Updates: Fifty-two (52) medications added to the 2025 Medicare Part D Drug plan formularies.

Category: Monthly Formulary changes
Published: Mar 27, 2025 02:33:00
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The March 2025 Medicare Part D prescription drug plan formulary (drug list) data is now online and included in our Formulary Browser and Q1Rx Drug Finder.

The March formulary updates include the addition of 95 new National Drug Codes (NDCs), representing 52 different prescription drugs, many with multiple strengths.

The formulary updates impact both stand-alone Medicare Part D plans (PDPs) and Medicare Advantage plans with drug coverage (MAPDs).


Highlights of the March 2025 Formulary updates include ten (10) newly-introduced brand-name drugs

The March drug data updates include twenty-nine (29) new brand-name drugs, ten (10) of which are newly introduced brand-name drugs, some with multiple strengths. These drugs include:
  • AQNEURSA®,
  • ATTRUBY®,
  • DANZITEN®,
  • IMKELDI®,
  • MIPLYFFA®,
  • REVUFORJ®,
  • TRYVIO®,
  • UNDECATREX®,
  • YORVIPATH®, and
  • ZEPBOUND®.

The March 2025 Formulary updates include one (1) newly-added generic drug

The March Medicare Part D drug data also includes twenty-three (23) new generic medications, one (1) of which is newly-introduced generic drug, FLURBIPROFEN [ANSAID®].
Please note that these new generic and brand-name drugs are not available on all Medicare Part D or Medicare Advantage drug plans - and you can review the chart to see the (often limited) number of plan formularies that now include these drugs.


Reminders about Medicare prescription drug plan formulary changes
  1. Medicare Part D plans (PDPs and MAPDs) can change their formulary or drug list during the year and may drop one of your formulary medication mid-year for specific Medicare-allowable reasons (such as a new generic drug is available), but there are steps you can take if your medication is no longer covered by your prescription drug plan.

  2. In most cases, your Medicare Part D plan will notify you if the plan drops a medication you are currently using.

Good to know: What is the NDC?

The NDC or National Drug Code is used to uniquely identify a particular drug, manufacturer, strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the drug manufacturer, the second set of number identifies the product and strength, and the third set of numbers identifies the packaging.  You can read more here: Q1FAQ.com/155


Summary of March 2025 NDC changes

There are many reasons for NDCs to be added to the Medicare Part D program, a summary for all 95 new March 2025 NDCs is as follows:

Reason for NDC Addition Occurrences
New Drug 19
New Drug and Strength 42
New Drug, Delivery Form and Strength 2
New Drug, Manufacturer and Strength 2
New Manufacturer and Strength 15
New Manufacturer, Delivery Form and Strength 4
New Strength 11
Grand Total 95

The following chart details the 95 new manufacturer / drug-strength / packaging combinations (NDCs) that were added to one or more Medicare Part D formularies in the most recent updates -- as you will notices, some drugs are only covered by a few Medicare plans.

You can click on the Drug Name below to go to our Q1Medicare.com Drug Finder (Q1Rx.com) and see the details of how this drug is covered by all Medicare Part D plans (PDPs) in Florida (our example state).  You can then change the state in our search form for details of drug coverage in your service area.


NDC Drug Name Number of
PDP Formularies*		 Number of
MAPD Formularies*		 Notes
61314033264 ADALIMUMAB-ADAZ(CF) 20MG/0.2ML SYRINGE [Hyrimoz] 3 18 New Strength
83853010101 AQNEURSA 1 GRAM GRANULE PACKET 0 18 New Drug
82228071228 ATTRUBY 356 MG TABLET 0 5 New Drug
00548835101 BAQSIMI 3 MG SPRAY ONE PACK 16 161 New Drug
00591283201 BEXAROTENE 75 MG CAPSULE [Targretin] 40 345 New Manufacturer, Delivery Form and Strength
68180043401 BROMFENAC SOD 0.075% EYE DROPS [BromSite] 9 172 New Drug
51672140204 CALCIPOTRIENE-BETAMETH DP SUSPENSION [Taclonex Scalp] 1 17 New Drug
58151007893 CARDURA XL 4 MG TABLET 24HR 0 3 New Strength
58151008301 CELEBREX 100 MG CAPSULE 0 5 New Strength
58151008401 CELEBREX 200 MG CAPSULE 0 5 New Strength
13668030760 CELECOXIB 50 MG CAPSULE [Celebrex] 39 344 New Manufacturer and Strength
62135080937 CIMETIDINE 300 MG/5 ML SOLUTION 4 107 New Manufacturer and Strength
64950026810 CLEMASTINE FUM 2.68 MG TABLET 2 38 New Drug
24338015401 DANZITEN 71 MG TABLET 37 302 New Drug and Strength
24338015501 DANZITEN 95 MG TABLET 37 302 New Drug and Strength
58151011001 DILANTIN 100 MG CAPSULE 8 58 New Manufacturer and Strength
58151011535 DILANTIN 125 MG/5 ML ORAL SUSPENSION 5 33 New Manufacturer, Delivery Form and Strength
66758008675 DUREZOL 0.05% EYE DROPS 0 4 New Drug
58151012693 EFFEXOR XR 75 MG CAPSULE ER 24HR 0 3 New Strength
64950021810 FLURBIPROFEN 100 MG TABLET [Ansaid] 39 331 New Drug
00049392010 GEODON 20 MG/ML VIAL 0 4 New Strength
00591084501 GLIPIZIDE ER 10 MG TABLET 24HR [Glucotrol XL] 40 345 New Manufacturer and Strength
61269083510 HYDREA 500 MG CAPSULE 0 3 New Drug
81927020101 IMKELDI 80 MG/ML SOLUTION 40 340 New Drug
58151014293 INSPRA 25 MG TABLET 0 3 New Drug and Strength
58151014393 INSPRA 50 MG TABLET 0 3 New Drug and Strength
65162008774 ITRACONAZOLE 10 MG/ML SOLUTION [Sporanox] 4 76 New Manufacturer, Delivery Form and Strength
72065000101 KEVEYIS 50 MG TABLET 0 12 New Drug
00115993178 LEVALBUTEROL 0.63 MG/3 ML SOL VIAL-NEB [Xopenex] 10 187 New Manufacturer and Strength
82347003004 LEVOTHYROXINE 100 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
82347003504 LEVOTHYROXINE 112 MCG CAPSULE [TIROSINT] 1 12 New Drug and Strength
82347004004 LEVOTHYROXINE 125 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
82347000504 LEVOTHYROXINE 13 MCG CAPSULE [TIROSINT] 1 9 New Drug and Strength
82347004504 LEVOTHYROXINE 137 MCG CAPSULE [TIROSINT] 1 9 New Drug and Strength
82347005004 LEVOTHYROXINE 150 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
82347005504 LEVOTHYROXINE 175 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
82347006004 LEVOTHYROXINE 200 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
82347001004 LEVOTHYROXINE 25 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
82347001504 LEVOTHYROXINE 50 MCG CAPSULE [TIROSINT] 1 14 New Drug and Strength
82347002004 LEVOTHYROXINE 75 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
82347002504 LEVOTHYROXINE 88 MCG CAPSULE [TIROSINT] 1 11 New Drug and Strength
58151015577 LIPITOR 10 MG TABLET 0 3 New Strength
58151015677 LIPITOR 20 MG TABLET 0 3 New Strength
58151015877 LIPITOR 80 MG TABLET 0 3 New Strength
00143914403 LIRAGLUTIDE 3-PAK 18 MG/3 ML PEN INJECTOR [VICTOZA] 1 65 New Drug
71921025096 LOFEXIDINE 0.18 MG TABLET [LUCEMYRA] 1 38 New Drug
58151024077 LYRICA 150 MG CAPSULE 0 3 New Manufacturer and Strength
58151024435 LYRICA 20 MG/ML ORAL SOLUTION 0 3 New Manufacturer and Strength
58151023677 LYRICA 25 MG CAPSULE 0 3 New Manufacturer and Strength
58151023777 LYRICA 50 MG CAPSULE 0 3 New Manufacturer and Strength
72542012401 MIPLYFFA 124 MG CAPSULE 0 60 New Drug and Strength
72542014701 MIPLYFFA 47 MG CAPSULE 0 60 New Drug and Strength
72542016201 MIPLYFFA 62 MG CAPSULE 0 60 New Drug and Strength
72542019301 MIPLYFFA 93 MG CAPSULE 0 60 New Drug and Strength
69097085107 NAPROXEN DR 375 MG TABLET [EC-Naprosyn] 36 320 New Manufacturer and Strength
58151031052 NITROSTAT 0.4 MG TABLET SUBLIGUAL 5 19 New Manufacturer and Strength
58151031101 NITROSTAT 0.6 MG TABLET SUBLIGUAL 5 19 New Manufacturer and Strength
51991097401 PENICILLAMINE 250 MG CAPSULE [Cuprimine] 4 22 New Drug
72888020101 POTASSIUM CL ER 15 MEQ TABLET 15 178 New Drug
61269051812 PULMICORT 180 MCG FLEXHALER AER POW BA 3 44 New Drug and Strength
61269050906 PULMICORT 90 MCG FLEXHALER AER POW BA 3 44 New Drug and Strength
73555050100 REVUFORJ 110 MG TABLET 40 342 New Drug and Strength
73555050200 REVUFORJ 160 MG TABLET 40 342 New Drug and Strength
82154078301 RUBRACA 200 MG TABLET 40 345 New Drug and Strength
82154078401 RUBRACA 250 MG TABLET 40 345 New Drug and Strength
82154078501 RUBRACA 300 MG TABLET 40 345 New Drug and Strength
69238202708 SPIRONOLACTONE 25 MG/5 ML ORAL SUSPENSION [CAROSPIR] 0 12 New Drug
70069051701 TIMOLOL 0.5% EYE DROP DAILY [Timoptic Ocumeter] 13 64 New Manufacturer and Strength
72888016330 TRAMADOL HCL 75 MG TABLET 1 6 New Strength
68682051384 TRETINOIN GEL MICRO 0.1% TUBE [Retin-A Micro] 4 31 New Manufacturer, Delivery Form and Strength
80491801203 TRYVIO 12.5 MG TABLET 0 3 New Drug
73352010522 UNDECATREX 200 MG CAPSULE 0 2 New Drug
61269048060 VALCYTE 450 MG TABLET 0 3 New Drug, Delivery Form and Strength
61269048510 VALCYTE 50 MG/ML SOLUTION RECON 0 3 New Drug, Delivery Form and Strength
67877075081 VANCOMYCIN 25 MG/ML ORAL SOLUTION RECON [FIRVANQ] 4 49 New Drug
53436001060 VELTASSA 1 GM POWDER PACKET 20 128 New Strength
00527260532 VENLAFAXINE HCL ER 225 MG TABLET 24HR 1 48 New Manufacturer and Strength
73362010001 YORVIPATH 168 MCG/0.56 ML PEN INJECTOR 1 23 New Drug and Strength
73362010101 YORVIPATH 294 MCG/0.98 ML PEN INJECTOR 1 23 New Drug and Strength
73362010201 YORVIPATH 420 MCG/1.4 ML PEN INJECTOR 1 23 New Drug and Strength
00002247180 ZEPBOUND 10 MG/0.5 ML PEN INJECTOR 0 5 New Drug and Strength
00002246080 ZEPBOUND 12.5 MG/0.5 ML PEN INJECTOR 0 5 New Drug and Strength
00002245780 ZEPBOUND 15 MG/0.5 ML PEN INJECTOR 0 5 New Drug and Strength
00002250680 ZEPBOUND 2.5 MG/0.5 ML PEN INJECTOR 0 5 New Drug and Strength
00002015204 ZEPBOUND 2.5 MG/0.5 ML VIAL 0 2 New Drug, Manufacturer and Strength
00002249580 ZEPBOUND 5 MG/0.5 ML PEN INJECTOR 0 5 New Drug and Strength
00002024304 ZEPBOUND 5 MG/0.5 ML VIAL 0 2 New Drug, Manufacturer and Strength
00002248480 ZEPBOUND 7.5 MG/0.5 ML PEN INJECTOR 0 5 New Drug and Strength
24979024007 ZESTRIL 10 MG TABLET 0 5 New Drug and Strength
24979023807 ZESTRIL 2.5 MG TABLET 0 5 New Drug and Strength
24979024107 ZESTRIL 20 MG TABLET 0 5 New Drug and Strength
24979024207 ZESTRIL 30 MG TABLET 0 5 New Drug and Strength
24979024307 ZESTRIL 40 MG TABLET 0 5 New Drug and Strength
24979023907 ZESTRIL 5 MG TABLET 0 5 New Drug and Strength
58151057493 ZOLOFT 25 MG TABLET 0 3 New Manufacturer and Strength




If your brand-name drug is no longer covered by your Medicare Part D plan, you can use the 30-day notice period (if notice is provided) to:
Learn more in our article: How a mid-year formulary change can affect your Medicare Part D drug coverage.

Our online Formulary Browser and Drug Finder

You can review any Medicare plan formulary using the Q1Medicare.com Formulary Browser found at: FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your Service Area using our Drug Finder found at: Q1Rx.com.

Additional Formulary Drug Change Articles:

Medicare Part D Plan Formulary (Drug Lists) Updates:
March 2025, June 2024, May 2024, April 2024, September 2023, August 2023, June 2023, May 2023, April 2023, March 2023, February 2023, August 2022, June 2022, May 2022, April 2022, March 2022, February 2022, August 2021, June 2021, May 2021, April 2021, September 2020, August 2020, June 2020, May 2020, April 2020, March 2020, September 2019, July 2019, June 2019, May 2019, April 2019, March 2019, August 2018, July 2018, June 2018, May 2018, April 2018, August 2017, July 2017, May 2017, April 2017, August 2016, July 2016, June 2016, April 2016, March 2016, October 2015, August 2015, July 2015, May 2015, April 2015, August 2014, May 2014, August 2013, June 2013, May 2013, April 2013, August 2012, July 2012, June 2012

Formulary Changes to the Top Medicare Drugs:
March 2025, June 2024, September 2023, September 2022, September 2021, September 2020, April 2020, September 2019, April 2019, August 2018, April 2018, August 2017, April 2017, August 2016, April 2016, October 2015, April 2015, August 2014, August 2013, April 2013

New Generic Equivalents Added to Formularies:
May 2024, June 2023, February 2023, August 2021, June 2021, May 2021, April 2021, September 2020, August 2020, June 2020, May 2020, April 2020, March 2020, September 2019, July 2019, June 2019, May 2019, April 2019, March 2019, August 2018, July 2018, April 2018, August 2017, July 2017, April 2017, March & April 2016, April & May 2015, August 2014, May 2014


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