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May 2021 Medicare Drug List Updates: Forty (40) medications added to 2021 Medicare Part D Drug plan formularies.

Category: Monthly Formulary Changes
Published: May, 21 2021 12:05:37
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We now have the recently released May 2021 Medicare Part D prescription drug plan formulary (drug lists) data online and included in our Formulary Browser and Q1Rx Drug Finder.

The May formulary updates include the addition of 40 new National Drug Codes (NDCs), representing 28 different prescription drugs, many with multiple strengths.

The formulary updates impact both stand-alone Medicare Part D plans (PDPs) and Medicare Advantage plans with drug coverage (MAPDs).


Highlights of the May 2021 Formulary update include six (6) newly-added brand-name drugs

The May drug data updates include 13 new brand-name drugs, six (6) of which are newly introduced brand-name drugs, some with multiple strengths. These drugs include:
  • BRONCHITOL®,
  • KLISYRI®,
  • LUPKYNIS®,
  • TEMIXYS®,
  • TEPMETKO®, and
  • VERQUVO®.

The May 2021 Formulary update includes nine (9) newly-added generic drugs

The May Medicare Part D drug data also includes 15 new generic medications, nine (9) of which are newly-introduced generic drugs.  These new generic drugs include:
  • DISULFIRAM [Antabuse®],
  • FLUTAMIDE [Eulexin®],
  • LUBIPROSTONE [Amitiza®],
  • LYLLANA [Vivelle-Dot®],
  • MELOXICAM [Vivlodex®],
  • NYMYO [VyLibra®],
  • PROCTO-MED HC [Proctozone-HC®],
  • TRI-NYMYO [Trinessa®], and
  • TYDEMY [Tydemy®].

You can see our article "May 2021 Drug List Updates: Fifteen (15) new generic drugs added to many Medicare Part D plan formularies." found at https://Q1News.com/896.html for more about coverage the new generics.

Please note that these new generic and brand-name drugs are not available on all Medicare Part D or Medicare Advantage drug plans - and you can review the chart to see the (often limited) number of plan formularies that now include these drugs.


Reminders about Medicare prescription drug plan formulary changes
  1. Medicare Part D plans (PDPs and MAPDs) can change their formulary or drug list during the year and may drop one of your formulary medication mid-year for specific Medicare-allowable reasons (such as a new generic drug is available), but there are steps you can take if your medication is no longer covered by your prescription drug plan.

  2. Your Medicare Part D plan will notify you if the plan drops a medication you are currently using.

Good to know: What is the NDC?

The NDC or National Drug Code is used to uniquely identify a particular drug, manufacturer, strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the drug manufacturer, the second set of number identifies the product and strength, and the third set of numbers identifies the packaging.  You can read more here: Q1FAQ.com/155


Summary of May 2021 NDC changes

There are many reasons for NDCs to be added to the Medicare Part D program, a summary for all 40 new May 2021 NDCs is as follows:

Reason for NDC Addition Occurrences
New Drug 15
New Drug and Strength 16
New Manufacturer 1
New Manufacturer and Delivery Form 1
New Manufacturer and Strength 2
New Manufacturer, Strength and Delivery Form 2
New Packaging 1
New Strength 2
Grand Total 40

The following chart details the 40 new manufacturer / drug-strength / packaging combinations (NDCs) that were added to one or more Medicare Part D formularies in the most recent updates -- as you will notices, some drugs are only covered by a few Medicare plans.

You can click on the Drug Name below to go to our Q1Medicare.com Drug Finder (Q1Rx.com) and see the details of how this drug is covered by all Medicare Part D plans (PDPs) in Florida (our example state).  You can then change the state in our search form for details of drug coverage in your service area.


NDC Drug Name Number of
PDP Formularies*		 Number of
MAPD Formularies*		 Notes
10122021256 BRONCHITOL 40 MG INHALE CAPSULE W/DEV 6 65 New Drug
00025281831 CALAN SR 180 MG TABLET 0 3 New Strength
00054035725 DISULFIRAM 500 MG TABLET [Antabuse] 64 365 New Drug
69238209203 EMTRICITABINE-TENOFV 100-150MG TABLET [Truvada] 68 395 New Drug and Strength
69238209303 EMTRICITABINE-TENOFV 133-200MG TABLET [Truvada] 68 395 New Drug and Strength
69238209403 EMTRICITABINE-TENOFV 167-250MG TABLET [Truvada] 68 395 New Drug and Strength
00093770456 EMTRICITABINE-TENOFV 200-300MG TABLET [Truvada] 68 395 New Drug and Strength
49884075313 FLUTAMIDE 125 MG CAPSULE [Eulexin] 68 398 New Drug
16110039105 KLISYRI 1% OINTMENT PACKET 1 29 New Drug
17478083005 LOTEPREDNOL 0.5% OPHTHALMC GEL DROPS [Lotemax] 9 190 New Manufacturer
00254302902 LUBIPROSTONE 24 MCG CAPSULE [Amitiza] 18 166 New Drug and Strength
00254302802 LUBIPROSTONE 8 MCG CAPSULE [Amitiza] 18 166 New Drug and Strength
75626000102 LUPKYNIS 7.9 MG CAPSULE 7 69 New Drug
65162012608 LYLLANA 0.025 MG PATCH TDSW [Vivelle-Dot] 39 305 New Drug and Strength
65162014808 LYLLANA 0.0375 MG PATCH TDSW [Vivelle-Dot] 39 305 New Drug and Strength
65162015008 LYLLANA 0.075 MG PATCH TDSW [Vivelle-Dot] 39 305 New Drug and Strength
65162014908 LYLLANA 0.05 MG PATCH TDSW [Vivelle-Dot] 39 305 New Drug and Strength
65162022808 LYLLANA 0.1 MG PATCH TDSW [Vivelle-Dot] 39 305 New Drug and Strength
00078097912 MAYZENT 0.25 MG STARTER PACK TABLET DS PK 20 224 New Packaging
68180018906 MELOXICAM 10 MG CAPSULE [Vivlodex] 0 8 New Drug and Strength
68180018806 MELOXICAM 5 MG CAPSULE [Vivlodex] 0 8 New Drug and Strength
16714085303 METOPROLOL SUCC ER 50 MG TABLET ER 24H [Toprol XL] 68 398 New Manufacturer and Strength
67877067001 MORPHINE SULFATE IR 15 MG TABLET [MSIR] 68 398 New Manufacturer, Strength and Delivery Form
67877067101 MORPHINE SULFATE IR 30 MG TABLET [MSIR] 68 398 New Manufacturer, Strength and Delivery Form
51862064506 NYMYO 0.25-0.035 MG (28) TABLET [VyLibra] 51 323 New Drug
70370302502 ONGENTYS 25 MG CAPSULE 2 51 New Strength
00126027216 PERIOGARD 0.12% ORAL RINSE MOUTHWASH [Perisol] 62 377 New Drug
69315031228 PROCTO-MED HC 2.5% CREAM CRM/PE APP [Proctozone-HC] 65 384 New Drug
71403000330 RHOFADE 1% CREAM (G) 0 5 New Drug
69102010501 ROWEEPRA 500 MG TABLET 63 309 New Drug
72606000201 TEMIXYS 300-300 MG TABLET 68 393 New Drug
10337016360 TEMOVATE 0.05% CREAM (G) 0 6 New Drug
44087500006 TEPMETKO 225 MG TABLET 68 389 New Drug
13668033101 TRAZODONE 100 MG TABLET [Desyrel] 68 398 New Manufacturer and Strength
51862064606 TRI-NYMYO 28 TABLET [Trinessa] 60 339 New Drug
68180090471 TYDEMY 3-0.03-0.451 MG TABLET [Tydemy] 20 135 New Drug
00006503001 VERQUVO 10 MG TABLET 4 34 New Drug and Strength
00006502802 VERQUVO 2.5 MG TABLET 4 34 New Drug and Strength
00006502902 VERQUVO 5 MG TABLET 4 34 New Drug and Strength
00069102902 XELJANZ 1 MG/ML SOLUTION 50 345 New Manufacturer and Delivery Form




Our online Formulary Browser and Drug Finder

You can review any Medicare plan formulary using the Q1Medicare.com Formulary Browser found at: FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your Service Area using our Drug Finder found at: Q1Rx.com.

Additional Formulary Drug Change Articles:

Medicare Part D Plan Formulary (Drug Lists) Updates:
September 2023, August 2023, June 2023, May 2023, April 2023, March 2023, February 2023, August 2022, June 2022, May 2022, April 2022, March 2022, February 2022, August 2021, June 2021, May 2021, April 2021, September 2020, August 2020, June 2020, May 2020, April 2020, March 2020, September 2019, July 2019, June 2019, May 2019, April 2019, March 2019, August 2018, July 2018, June 2018, May 2018, April 2018, August 2017, July 2017, May 2017, April 2017, August 2016, July 2016, June 2016, April 2016, March 2016, October 2015, August 2015, July 2015, May 2015, April 2015, August 2014, May 2014, August 2013, June 2013, May 2013, April 2013, August 2012, July 2012, June 2012

Formulary Changes to the Top Medicare Drugs:
September 2023, September 2022, September 2021, September 2020, April 2020, September 2019, April 2019, August 2018, April 2018, August 2017, April 2017, August 2016, April 2016, October 2015, April 2015, August 2014, August 2013, April 2013

New Generic Equivalents Added to Formularies:
June 2023, February 2023, August 2021, June 2021, May 2021, April 2021, September 2020, August 2020, June 2020, May 2020, April 2020, March 2020, September 2019, July 2019, June 2019, May 2019, April 2019, March 2019, August 2018, July 2018, April 2018, August 2017, July 2017, April 2017, March & April 2016, April & May 2015, August 2014, May 2014


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