The NDC uniquely identifies a particular manufacturer, drug-strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the manufacturer, the second set of number identifies the drug and strength, and the third set of numbers identifies the packaging.
This article highlights the change for some of the "top Medicare drugs", including their generic equivalents. The generics included are Atorvastatin [Lipitor®] , Clopidogrel [Plavix®], Escitalopram [Lexapro®], Esomeprazole Sodium [Nexium®], FLUTICASONE-SALMETEROL [Advair®], Pioglitazone [Actos®], Quetiapine Fumarate [Seroquel®], Risedronate Sodium [Actonel®], and Valsartan-HCTZ [Diovan HCT®]. The changes to the number of formularies covering these medications looks as follows:
| Count of Formularies Covering the Top Medicare Drugs Program-wide | ||||||||||||
| Formulary Count* | ||||||||||||
| Drug Name | 2019 End** | 2020 End** | 2021 End** | 2022 End** | 2023 End** | 2024 End** |
2025 Start** |
August | ||||
| ACTONEL 35 MG TABLET | 8 | 11 | 3 | 3 | 2 | 1 | 0 | 0 | ||||
| ACTOS 30 MG TABLET | 16 | 15 | 13 | 5 | 3 | 4 | 3 | 3 | ||||
| ADVAIR DISKUS MIS 250/50 | 361 | 312 | 289 | 349 | 316 | 15 | 15 | 15 | ||||
| ATORVASTATIN 10 MG TABLET [Lipitor] | 406 | 454 | 456 | 458 | 450 | 421 | 383 | 382 | ||||
| CLOPIDOGREL 75 MG TABLET [Plavix] | 406 | 454 | 456 | 458 | 450 | 421 | 383 | 382 | ||||
| DIOVAN HCT 160/12.5MG TABLET | 17 | 18 | 13 | 5 | 3 | 4 | 3 | 3 | ||||
| ESCITALOPRAM 10 MG TABLET [Lexapro] | 406 | 454 | 456 | 458 | 450 | 421 | 383 | 382 | ||||
| ESOMEPRAZOLE MAG DR 40 MG CAPSULE [Nexium] | 309 | 353 | 376 | 419 | 414 | 389 | 356 | 357 | ||||
| FLUTICASONE-SALMETEROL 250-50 INHALER [Advair] | 122 | 216 | 221 | 174 | 196 | 398 | 359 | 359 | ||||
| LANTUS 100U/ML VIAL | 306 | 364 | 363 | 362 | 392 | 354 | 297 | 300 | ||||
| LEXAPRO 10MG TABLET | 14 | 12 | 13 | 5 | 4 | 4 | 3 | 3 | ||||
| LIPITOR 10MG TABLET | 19 | 16 | 11 | 3 | 3 | 4 | 3 | 3 | ||||
| NEXIUM DR 40 MG CAPSULE | 19 | 10 | 11 | 3 | 3 | 4 | 3 | 3 | ||||
| PIOGLITAZONE HCL 30 MG TABLET [Actos] | 406 | 454 | 456 | 458 | 450 | 421 | 383 | 382 | ||||
| PLAVIX 75 MG TABLET | 75 | 10 | 11 | 3 | 3 | 4 | 3 | 3 | ||||
| QUETIAPINE FUMARATE 25 MG TABLET [Seroquel] | 406 | 454 | 456 | 458 | 450 | 421 | 383 | 382 | ||||
| RISEDRONATE SODIUM 35 MG TABLET [Actonel] | 287 | 335 | 360 | 368 | 355 | 339 | 273 | 271 | ||||
| SEROQUEL 25MG TABLET | 9 | 10 | 11 | 3 | 3 | 4 | 3 | 3 | ||||
| VALSARTAN-HCTZ 160-12.5 MG TABLET [Diovan HCT] | 403 | 451 | 451 | 454 | 448 | 420 | 382 | 381 | ||||
**The ending CMS formulary datasets are the respective September dataset. The starting 2025 CMS formulary dataset is dated October, 2024.
Learn more in our article: How a mid-year formulary change can affect your Medicare Part D drug coverage.
You can review any Medicare plan formulary using the on this site FormularyBrowser at FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your service area using our on this site.