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April 2022 Medicare Drug List Updates: Seventy (70) medications added to the 2022 Medicare Part D Drug plan formularies.

Monthly Formulary changes · published Apr 19, 2022

The April 2022 Medicare Part D prescription drug plan formulary (drug list) data is now online and included in our Formulary Browser and the drug finder Drug Finder.

The April formulary updates include the addition of 70 new National Drug Codes (NDCs), representing 42 different prescription drugs, many with multiple strengths.

The formulary updates impact both stand-alone Medicare Part D plans (PDPs) and Medicare Advantage plans with drug coverage (MAPDs).


Highlights of the April 2022 Formulary updates include six (6) newly-added brand-name drugs

The April drug data updates include nineteen (19) new brand-name drugs, six (6) of which are newly introduced brand-name drugs, some with multiple strengths. These drugs include:
  • ADBRY®,
  • BYLVAY®,
  • CORTROPHIN®,
  • SKYTROFA®,
  • TARPEYO®, and
  • VOXZOGO®.

The April 2022 Formulary updates include five (5) newly-added generic drugs

The April Medicare Part D drug data also includes twenty-three (23) new generic medications, five (5) of which are newly-introduced generic drugs.  These new generic drugs include:
  • BRIMONIDINE-TIMOLOL [COMBIGAN®],
  • ESTRADIOL VALERATE [DELESTROGEN®],
  • LIDOCAINE [SOLUPAK®],
  • LIDOCAINE HCL [XYLOCAINE®], and
  • POTASSIUM CL [PROAMP®].

Please note that these new generic and brand-name drugs are not available on all Medicare Part D or Medicare Advantage drug plans - and you can review the chart to see the (often limited) number of plan formularies that now include these drugs.


Reminders about Medicare prescription drug plan formulary changes
  1. Medicare Part D plans (PDPs and MAPDs) can change their formulary or drug list during the year and may drop one of your formulary medication mid-year for specific Medicare-allowable reasons (such as a new generic drug is available), but there are steps you can take if your medication is no longer covered by your prescription drug plan.

  2. Your Medicare Part D plan will notify you if the plan drops a medication you are currently using.

Good to know: What is the NDC?

The NDC or National Drug Code is used to uniquely identify a particular drug, manufacturer, strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the drug manufacturer, the second set of number identifies the product and strength, and the third set of numbers identifies the packaging.  You can read more on this site


Summary of April 2022 NDC changes

There are many reasons for NDCs to be added to the Medicare Part D program, a summary for all 70 new April 2022 NDCs is as follows:

Reason for NDC Addition Occurrences
New Delivery Form2
New Drug18
New Drug and Strength31
New Drug, Delivery Form and Strength1
New Manufacturer and Delivery Form1
New Manufacturer and Strength9
New Manufacturer, Strength and Delivery Form3
New Strength5
Grand Total70

The following chart details the 70 new manufacturer / drug-strength / packaging combinations (NDCs) that were added to one or more Medicare Part D formularies in the most recent updates -- as you will notices, some drugs are only covered by a few Medicare plans.

You can click on the Drug Name below to go to our on this site Drug Finder ( on this site) and see the details of how this drug is covered by all Medicare Part D plans (PDPs) in Florida (our example state).  You can then change the state in our search form for details of drug coverage in your service area.
NDC Drug Name Number of
PDP Formularies*		 Number of
MAPD Formularies*		 Notes
72143023130ACCUTANE 10 MG CAPSULE [ZENATANE]52360New Strength
50222034604ADBRY 150 MG/ML SYRINGE116New Drug
57841120001AEMCOLO DR 194 MG TABLET DR017New Drug
78206011201ASMANEX HFA 100 MCG INHALER HFA AER AD26188New Drug and Strength
78206011301ASMANEX HFA 200 MCG INHALER HFA AER AD26188New Drug and Strength
78206011101ASMANEX HFA 50 MCG INHALER HFA AER AD26185New Drug and Strength
78206011501ASMANEX TWISTHALER 110 MCG #30 AER POW BA26187New Drug and Strength
78206011401ASMANEX TWISTHALER 220 MCG #120 AER POW BA26187New Drug and Strength
78206011404ASMANEX TWISTHALER 220 MCG #30 AER POW BA26187New Drug and Strength
78206011402ASMANEX TWISTHALER 220 MCG #60 AER POW BA26187New Drug and Strength
51672134004BETAMETHASONE DP AUG 0.05% LOTION [Diprolene]53379New Manufacturer and Delivery Form
61958250501BIKTARVY 30-120-15 MG TABLET63404New Strength
60505622500BRIMONIDINE-TIMOLOL 0.2%-0.5% DROPS [Combigan]8147New Drug
74528012001BYLVAY 1,200 MCG CAPSULE499New Drug and Strength
74528002001BYLVAY 200 MCG PELLET DSP CP499New Drug and Strength
74528004001BYLVAY 400 MCG CAPSULE499New Drug and Strength
78206011901CLARINEX 5 MG TABLET01New Drug
78206012001CLARINEX-D 12 HR 2.5-120 MG TABLET TBMP 12HR118New Drug
78670010001CORGARD 20 MG TABLET21New Manufacturer and Strength
78670010101CORGARD 40 MG TABLET21New Manufacturer and Strength
62559086015CORTROPHIN GEL 400 UNIT/5 ML VIAL171New Drug
00310758090CRESTOR 20 MG TABLET21New Strength
00310759030CRESTOR 40 MG TABLET21New Strength
00172640649CROMOLYN 20 MG/2 ML NEB SOLN AMPUL-NEB [Intal]63359New Drug
71800000301CYCLOBENZAPRINE 7.5 MG TABLET [Fexmid]279New Drug
68180094804DESOXIMETASONE 0.05% OINTMENT [Topicort LP]8109New Delivery Form
57664062388DEXMETHYLPHENIDATE ER 15 MG CPBP 50-50 [Focalin XR]7120New Manufacturer and Strength
57664062588DEXMETHYLPHENIDATE ER 30 MG CPBP 50-50 [Focalin XR]7120New Manufacturer and Strength
78206012402DIPROLENE 0.05% OINTMENT21New Drug
78206012701DULERA 100 MCG-5 MCG INHALER HFA AER AD20146New Drug and Strength
78206012601DULERA 200 MCG-5 MCG INHALER HFA AER AD20146New Drug and Strength
78206012501DULERA 50 MCG-5 MCG INHALER HFA AER AD20143New Drug and Strength
45802046653ECONAZOLE NITRATE 1% CREAM (G) [Spectazole]39299New Drug
63739005366ERYTHROMYCIN 2% GEL [Erygel]27249New Drug
00517044001ESTRADIOL VALERATE 200 MG/5 ML VIAL [Delestrogen]34297New Drug
00713022360FLUOCINOLONE 0.01% CREAM (G)51393New Drug
51862015860FLURANDRENOLIDE 0.05% OINTMENT [Cordran]015New Manufacturer and Strength
68180095102HYDROCORTISONE BUTYR 0.1% LOTION [Locoid]256New Delivery Form
67877047379LIDOCAINE 5% OINTMENT [SOLUPAK]42346New Manufacturer, Strength and Delivery Form
00054350547LIDOCAINE HCL 4% SOLUTION [Xylocaine]53368New Manufacturer, Strength and Delivery Form
51862061501MORPHINE SULFATE IR 15 MG TABLET [MSIR]63404New Manufacturer and Strength
51862061701MORPHINE SULFATE IR 30 MG TABLET [MSIR]63404New Manufacturer and Strength
00093216568NALOXONE HCL 4 MG NASAL SPRAY [Narcan]57369New Manufacturer, Strength and Delivery Form
64380083622NYSTATIN-TRIAMCINOLONE OINTMENT [Mytrex]39264New Drug
59212070012ORAPRED ODT 10 MG TABLET RAPDIS09New Drug and Strength
59212070112ORAPRED ODT 15 MG TABLET RAPDIS07New Drug and Strength
59212070212ORAPRED ODT 30 MG TABLET RAPDIS07New Drug and Strength
66992012814OTOVEL 0.3%-0.025% EAR DROPS VIAL12New Drug
63323096730POTASSIUM CL 60 MEQ/30 ML CONC VIAL [PROAMP]52380New Manufacturer and Strength
70954004110RIFABUTIN 150 MG CAPSULE [Mycobutin]63404New Drug
65862068730RITONAVIR 100 MG TABLET [Norvir]63404New Drug
78206017201SINGULAIR 10 MG TABLET21New Drug and Strength
78206017001SINGULAIR 4 MG CHEWABLE TABLET21New Drug and Strength
78206017101SINGULAIR 4 MG GRANULES GRAN PACK21New Drug, Delivery Form and Strength
78206017301SINGULAIR 5 MG CHEWABLE TABLET21New Drug and Strength
73362001001SKYTROFA 11 MG CARTRIDGE027New Drug and Strength
73362001101SKYTROFA 13.3 MG CARTRIDGE027New Drug and Strength
73362000301SKYTROFA 3 MG CARTRIDGE027New Drug and Strength
73362000401SKYTROFA 3.6 MG CARTRIDGE027New Drug and Strength
73362000501SKYTROFA 4.3 MG CARTRIDGE027New Drug and Strength
73362000601SKYTROFA 5.2 MG CARTRIDGE027New Drug and Strength
73362000701SKYTROFA 6.3 MG CARTRIDGE027New Drug and Strength
73362000801SKYTROFA 7.6 MG CARTRIDGE027New Drug and Strength
73362000901SKYTROFA 9.1 MG CARTRIDGE027New Drug and Strength
00338005403SODIUM CHLORIDE 3% IV SOLUTION35303New Strength
81749000401TARPEYO DR 4 MG CAPSULE DR420New Drug
70752012905TRIAMCINOLONE 0.025% LOTION [Kenalog]52393New Manufacturer and Strength
68135008236VOXZOGO 0.4 MG VIAL033New Drug and Strength
68135011966VOXZOGO 0.56 MG VIAL033New Drug and Strength
68135018193VOXZOGO 1.2 MG VIAL033New Drug and Strength
Our online Formulary Browser and Drug Finder

You can review any Medicare plan formulary using the on this site Formulary Browser found at: FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your Service Area using our Drug Finder found at on this site.

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