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February 2022 Medicare Drug List Updates: Eighty-Eight (88) medications added to 2022 Medicare Part D Drug plan formularies.

Monthly Formulary changes · published Feb 28, 2022

The recently released February 2022 Medicare Part D prescription drug plan formulary (drug lists) data is now online and included in our Formulary Browser and the drug finder Drug Finder.

The February formulary updates include the addition of 88 new National Drug Codes (NDCs), representing 59 different prescription drugs, many with multiple strengths.

The formulary updates impact both stand-alone Medicare Part D plans (PDPs) and Medicare Advantage plans with drug coverage (MAPDs).


Highlights of the February 2022 Formulary update include nine (9) newly-added brand-name drugs

The February drug data updates include twenty-six (26) new brand-name drugs, nine (9) of which are newly introduced brand-name drugs, some with multiple strengths. These drugs include:
  • INVEGA IHAFYERA®,
  • LOREEV XR®,
  • LYBALVI®,
  • PENTACEL®,
  • TAVNEOS®,
  • TRUSELTIQ®,
  • TYRVAYA®,
  • WELIREG®, and
  • WINLEVI®.

The February 2022 Formulary update includes eight (8) newly-added generic drugs

The February Medicare Part D drug data also includes thirty-three (33) new generic medications, eight (8) of which are newly-introduced generic drugs.  These new generic drugs include:
  • INSULIN GLARGINE-YFGN [Semglee®],
  • NEBIVOLOL [Bystolic®],
  • PAROXETINE HCL [Paxil®],
  • SAJAZIR®],
  • TAYSOFY [Taytulla®],
  • TRIMETHOPRIM [Proloprim®],
  • TRITOCIN [Trianex®], and
  • VARENICLINE [Chantix®].

Please note that these new generic and brand-name drugs are not available on all Medicare Part D or Medicare Advantage drug plans - and you can review the chart to see the (often limited) number of plan formularies that now include these drugs.


Reminders about Medicare prescription drug plan formulary changes
  1. Medicare Part D plans (PDPs and MAPDs) can change their formulary or drug list during the year and may drop one of your formulary medication mid-year for specific Medicare-allowable reasons (such as a new generic drug is available), but there are steps you can take if your medication is no longer covered by your prescription drug plan.

  2. Your Medicare Part D plan will notify you if the plan drops a medication you are currently using.

Good to know: What is the NDC?

The NDC or National Drug Code is used to uniquely identify a particular drug, manufacturer, strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the drug manufacturer, the second set of number identifies the product and strength, and the third set of numbers identifies the packaging.  You can read more on this site


Summary of February 2022 NDC changes

There are many reasons for NDCs to be added to the Medicare Part D program, a summary for all 88 new February 2022 NDCs is as follows:

Reason for NDC Addition Occurrences
New Delivery Form and Strength 3
New Drug 32
New Drug and Strength 30
New Manufacturer and Delivery Form 1
New Manufacturer and Strength 14
New Strength 8
Grand Total 88

The following chart details the 88 new manufacturer / drug-strength / packaging combinations (NDCs) that were added to one or more Medicare Part D formularies in the most recent updates -- as you will notices, some drugs are only covered by a few Medicare plans.

You can click on the Drug Name below to go to our on this site Drug Finder ( on this site) and see the details of how this drug is covered by all Medicare Part D plans (PDPs) in Florida (our example state).  You can then change the state in our search form for details of drug coverage in your service area.
NDC Drug Name Number of
PDP Formularies*		 Number of
MAPD Formularies*		 Notes
43598033960 ASPIRIN-DIPYRIDAM ER 25-200 MG CPMP 12HR [Aggrenox] 58 404 New Drug
68382012001 AZATHIOPRINE 100 MG TABLET [Azasan] 15 175 New Drug and Strength
68382011901 AZATHIOPRINE 75 MG TABLET [Azasan] 15 175 New Drug and Strength
00025271231 CALAN SR 120 MG TABLET 2 3 New Strength
16714006701 CARBIDOPA 25 MG TABLET [Lodosyn] 36 287 New Drug
42227008101 CINRYZE 500 UNIT VIAL 37 255 New Drug
42195012814 CIPROFLOX-FLUOCINLN 0.3-0.025% VIAL [OTOVEL] 3 42 New Drug
00078105697 COSENTYX 75 MG/0.5 ML SYRINGE 40 215 New Strength
44118071060 DESRX 0.05% GEL [Desonate] 6 53 New Drug
52536051503 DEXTROAMPHETAMINE 15 MG TABLET [Zenzedi] 17 144 New Manufacturer and Strength
52536052003 DEXTROAMPHETAMINE 20 MG TABLET [Zenzedi] 17 144 New Manufacturer and Strength
52536053003 DEXTROAMPHETAMINE 30 MG TABLET [Zenzedi] 17 144 New Manufacturer and Strength
74157000760 DICLOFENAC POT 25 MG TABLET [Lofena] 2 20 New Drug
69097034135 DIFLUPREDNATE 0.05% EYE DROPS [Durezol] 35 293 New Drug
62135062560 DOXYCYCLINE 50 MG TABLET [TARGADOX] 7 45 New Drug
69452023746 ENALAPRIL 1 MG/ML ORAL SOLUTION [Epaned] 2 38 New Drug
13668058601 ERYTHROMYCIN DR 250 MG TABLET [Ery-Tab] 53 300 New Manufacturer and Strength
00378000585 EVEROLIMUS 2 MG TABLET FOR SUSP [Afinitor DISPERZ] 63 399 New Manufacturer and Strength
00378000685 EVEROLIMUS 3 MG TABLET FOR SUSP [Afinitor DISPERZ] 63 402 New Manufacturer and Strength
00378000785 EVEROLIMUS 5 MG TABLET FOR SUSP [Afinitor DISPERZ] 63 402 New Manufacturer and Strength
51991082428 EVEROLIMUS 10 MG TABLET [Afinitor] 60 389 New Manufacturer and Strength
73116010006 FARYDAK 10 MG CAPSULE 63 404 New Drug and Strength
73116010106 FARYDAK 15 MG CAPSULE 63 404 New Drug and Strength
73116010206 FARYDAK 20 MG CAPSULE 63 404 New Drug and Strength
68180074606 FENOFIBRATE 90 MG CAPSULE [Antara] 0
 29 New Strength
10122010305 FERRIPROX 1,000 MG (3X/DAY) TABLET 12 231 New Delivery Form and Strength
10122010010 FERRIPROX 500 MG TABLET 7 47 New Delivery Form and Strength
00049035260 GEODON 20 MG CAPSULE 2 1 New Strength
00049035660 GEODON 60 MG CAPSULE 2 1 New Strength
00049035860 GEODON 80 MG CAPSULE 2 1 New Strength
00115180402 HYDROXYZINE PAM 50 MG CAPSULE [Vistaril] 34 324 New Drug
49502039380 INSULIN GLARGINE-YFGN U100 VIAL [Semglee] 0
 7 New Drug and Strength
49502039475 INSULIN GLARGINE-YFGN U100 INSULN PEN [Semglee] 0
 7 New Drug and Strength
50458061101 INVEGA HAFYERA 1,092 MG/3.5 ML SYRINGE 50 303 New Drug and Strength
50458061201 INVEGA HAFYERA 1,560 MG/5 ML SYRINGE 50 303 New Drug and Strength
16252053901 ISRADIPINE 2.5 MG CAPSULE [DynaCirc] 31 328 New Drug and Strength
16252054001 ISRADIPINE 5 MG CAPSULE [DynaCirc] 31 328 New Drug and Strength
00187410010 LIBRAX CAPSULE 0
 1 New Drug
52427065830 LOREEV XR 1 MG CAPSULE ER 24H 0
 3 New Drug and Strength
52427066330 LOREEV XR 2 MG CAPSULE ER 24H 0
 3 New Drug and Strength
52427066730 LOREEV XR 3 MG CAPSULE ER 24H 0
 3 New Drug and Strength
65757065242 LYBALVI 10-10 MG TABLET 47 290 New Drug and Strength
65757065342 LYBALVI 15-10 MG TABLET 47 290 New Drug and Strength
65757065442 LYBALVI 20-10 MG TABLET 47 290 New Drug and Strength
65757065142 LYBALVI 5-10 MG TABLET 47 290 New Drug and Strength
16714024530 MESALAMINE 1,000 MG SUPP.RECT [Canasa] 50 356 New Drug
64980022301 METHYLPHENIDATE 10 MG CHEWABLE TABLET [Methylin] 9 153 New Manufacturer and Strength
64980022201 METHYLPHENIDATE 5 MG CHEWABLE TABLET [Methylin] 9 152 New Manufacturer and Strength
00469502099 MYRBETRIQ ER 8 MG/ML SUSP ER REC 47 251 New Delivery Form and Strength
71776000515 NATACYN 5% EYE DROPS/EYE DROPPER 63 404 New Drug
62559027730 NEBIVOLOL 10 MG TABLET [Bystolic] 42 362 New Drug and Strength
62559027530 NEBIVOLOL 2.5 MG TABLET [Bystolic] 42 362 New Drug and Strength
62559027830 NEBIVOLOL 20 MG TABLET [Bystolic] 42 362 New Drug and Strength
62559027630 NEBIVOLOL 5 MG TABLET [Bystolic] 42 362 New Drug and Strength
31722094801 OXYCODONE-ACETAMINOPHN 2.5-325 TABLET [Percocet] 61 395 New Manufacturer and Strength
59212060122 PANRETIN 0.1% GEL 63 404 New Drug
70954031910 PAROXETINE HCL 10 MG/5 ML ORAL SUSPENSION [Paxil] 63 402 New Drug
49281051105 PENTACEL VIAL KIT 63 384 New Drug
63323032112 POLYMYXIN B SULFATE VIAL 11 189 New Drug
00121077708 PREDNISOLONE 20 MG/5 ML SOLUTION [Veripred-20] 7 153 New Drug
00023530105 RESTASIS MULTIDOSE 0.05% EYE DROPS 60 395 New Drug
70709001303 SAJAZIR 30 MG/3 ML SYRINGE 58 343 New Drug
49502025080 SEMGLEE (YFGN) 100 UNIT/ML VIAL 0
 3 New Drug and Strength
49502025175 SEMGLEE (YFGN) 100 UNIT/ML INSULN PEN 0
 3 New Drug and Strength
52427066430 SERTRALINE 150 MG CAPSULE 4 73 New Manufacturer and Strength
52427067230 SERTRALINE 200 MG CAPSULE 4 73 New Manufacturer and Strength
73556016802 TAVNEOS 10 MG CAPSULE 7 74 New Drug
65162055858 TAYSOFY 1 MG-20 MCG CAPSULE [Taytulla] 11 99 New Drug
70199001730 THALITONE 15 MG TABLET 0
 6 New Drug
51862089603 TILIA FE 28 TABLET [Tri-Legest Fe] 48 264 New Drug
42799020801 TINIDAZOLE 500 MG TABLET [Tindamax] 20 238 New Manufacturer and Strength
49502040124 TOBI PODHALER 28 MG INHALE CAPSULE W/DEV 11 172 New Drug
44118071115 TRITOCIN 0.05% OINTMENT [Trianex] 5 31 New Drug
51862048601 TRIMETHOPRIM 100 MG TABLET [Proloprim] 63 404 New Drug
72730011101 TRUSELTIQ 100 MG DAILY DOSE PK CAPSULE 63 404 New Drug and Strength
72730010101 TRUSELTIQ 125 MG DAILY DOSE PK CAPSULE 63 404 New Drug and Strength
72730050601 TRUSELTIQ 50 MG DAILY DOSE PK CAPSULE 63 404 New Drug and Strength
72730020201 TRUSELTIQ 75 MG DAILY DOSE PK CAPSULE 63 404 New Drug and Strength
73521003002 TYRVAYA 0.03 MG NASAL SPRAY METR 0
 3 New Drug
63323031461 VANCOMYCIN HCL 10 GM VIAL [Vancocin] 59 380 New Drug
49884015576 VARENICLINE 0.5 MG TABLET [Chantix] 61 396 New Drug and Strength
49884015676 VARENICLINE 1 MG TABLET [Chantix] 63 396 New Drug and Strength
00078093926 VIGAMOX 0.5% EYE DROPS 2 1 New Drug
00006533101 WELIREG 40 MG TABLET 63 404 New Drug
47335099436 WINLEVI 1% CREAM (G) 0
 10 New Drug
50242087701 XOFLUZA 80 MG TABLET 41 307 New Strength
73562011301 ZENPEP DR 3,000 UNIT CAPSULE DR 54 376 New Strength
45802071100 ZOLMITRIPTAN 5 MG NASAL SPRAY [Zomig] 1 69 New Manufacturer and Delivery Form
Our online Formulary Browser and Drug Finder

You can review any Medicare plan formulary using the on this site Formulary Browser found at: FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your Service Area using our Drug Finder found at on this site.

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