The June formulary updates include the addition of 132 new National Drug Codes (NDCs), representing 97 different prescription drugs, many with multiple strengths.
The formulary updates impact both stand-alone Medicare Part D plans (PDPs) and Medicare Advantage plans with drug coverage (MAPDs).
Highlights of the June 2025 Formulary updates include four (4) newly-introduced brand-name drugs
The June drug data updates include eleven (11) new brand-name drugs, four (4) of which are newly introduced brand-name drugs, some with multiple strengths. These drugs include:
- CRENESSITY®,
- JOURNAVX®,
- STEQEYMA®, and
- VIVOTIF®.
The June 2025 Formulary updates include ten (10) newly-added generic drugs
The June Medicare Part D drug data also includes eighty-six (86) new generic medications, ten (10) of which are newly-introduced generic drugs. These drugs include:
- ACETAMINOPHEN/CODEINE [Tylenol with Codeine No.4®],
- BACLOFEN [OZOBAX®],
- CLOBETASOL [Clodan®],
- FEIRZA 1.5/30 [Microgestin Fe 1.5/30®],
- FEIRZA 1/20 [Tarina Fe 1/20®],
- FLUTICASONE [Flonase Childrens Allergy®],
- GRISEOFULVIN ULTRA [Fulvicin P/G®],
- MEMANTINE-DONEPEZIL [Namzaric®],
- SELARSDI [Yesintek®], and
- XARAH FE [Xarah Fe®].
Reminders about Medicare prescription drug plan formulary changes
- Medicare Part D plans (PDPs and MAPDs) can change their formulary or drug list during the year and may drop one of your formulary medication mid-year for specific Medicare-allowable reasons (such as a new generic drug is available), but there are steps you can take if your medication is no longer covered by your prescription drug plan.
- In most cases, your Medicare Part D plan
will notify you if the plan drops a medication you are currently using.
The NDC or National Drug Code is used to uniquely identify a particular drug, manufacturer, strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the drug manufacturer, the second set of number identifies the product and strength, and the third set of numbers identifies the packaging. You can read more on this site
Summary of June 2025 NDC changes
There are many reasons for NDCs to be added to the Medicare Part D program, a summary for all 132 new June 2025 NDCs is as follows:
| Reason for NDC Addition | Occurrences |
| New Delivery Form | 3 |
| New Delivery Form and Strength | 1 |
| New Drug | 30 |
| New Drug and Delivery Form | 5 |
| New Drug and Strength | 24 |
| New Drug, Delivery Form and Strength | 1 |
| New Manufacturer | 3 |
| New Manufacturer and Delivery Form | 7 |
| New Manufacturer and Strength | 31 |
| New Manufacturer, Delivery Form and Strength | 8 |
| New Strength | 19 |
| Grand Total | 132 |
The following chart details the 132 new manufacturer / drug-strength / packaging combinations (NDCs) that were added to one or more Medicare Part D formularies in the most recent updates -- as you will notices, some drugs are only covered by a few Medicare plans.
You can click on the Drug Name below to go to our on this site Drug Finder ( on this site) and see the details of how this drug is covered by all Medicare Part D plans (PDPs) in Florida (our example state). You can then change the state in our search form for details of drug coverage in your service area.
| NDC | Drug Name | Number of PDP Formularies* |
Number of MAPD Formularies* |
Notes |
| 13107005999 | ACETAMINOPHEN-COD #3 TABLET [Tylenol with Codeine No.3] | 40 | 344 | New Drug and Strength |
| 71930005612 | ACETAMINOPHEN-COD #4 TABLET [Tylenol with Codeine No.4] | 40 | 344 | New Drug and Strength |
| 83257002042 | ADALIMUMAB-FKJP(CF) 20 MG SYRINGEKIT [Hulio] | 0 | 4 | New Drug and Strength |
| 83257002232 | ADALIMUMAB-FKJP(CF) 40 MG PEN INJECTOR KIT [Idacio] | 0 | 4 | New Drug, Delivery Form and Strength |
| 83257002142 | ADALIMUMAB-FKJP(CF) 40 MG SYRINGEKIT [Idacio] | 0 | 4 | New Drug and Strength |
| 60219174903 | ATROPINE 1% EYE DROPS [Isopto Atropine] | 39 | 337 | New Drug |
| 72888010324 | BACLOFEN 5 MG/5 ML SOLUTION [OZOBAX] | 0 | 2 | New Drug |
| 66993089749 | BETAMETHASONE DP AUG 0.05% OINTMENT [Diprolene] | 40 | 340 | New Manufacturer and Delivery Form |
| 54879000460 | BETAMETHASONE VA 0.1% LOTION [Valisone] | 40 | 342 | New Manufacturer and Delivery Form |
| 00713032737 | BETAMETHASONE VALER 0.1% OINTMENT [Valisone] | 40 | 344 | New Delivery Form |
| 60505058304 | BIMATOPROST 0.03% EYE DROPS [Lumigan] | 13 | 175 | New Drug |
| 82182045505 | BRIMONIDINE-TIMOLOL 0.2%-0.5% DROPS [Combigan] | 27 | 221 | New Drug |
| 68682046410 | BRINZOLAMIDE 1% EYE DROPS W/DROPPER [Azopt] | 22 | 243 | New Drug |
| 68382052701 | BUMETANIDE 2 MG TABLET [Bumex] | 40 | 344 | New Manufacturer and Strength |
| 69238120202 | BUPRENORPHINE 5 MCG/HR PATCH [Butrans] | 9 | 242 | New Strength |
| 42858050203 | BUPRENORPHINE 8 MG TABLET SUBLIGUAL [Subutex] | 40 | 344 | New Manufacturer and Strength |
| 68462050165 | CALCIPOTRIENE 0.005% CREAM (G) [Dovonex] | 35 | 325 | New Delivery Form |
| 16571068901 | CARBIDOPA-LEVODOPA 50 MG-ENTA TABLET [Stalevo] | 24 | 265 | New Drug and Strength |
| 16571069001 | CARBIDOPA-LEVODOPA 75 MG-ENTA TABLET [Stalevo] | 24 | 265 | New Drug and Strength |
| 16571069101 | CARBIDOPA-LEVODOPA 100 MG-ENTA TABLET [Stalevo] | 24 | 265 | New Drug and Strength |
| 16571069201 | CARBIDOPA-LEVODOPA 125 MG-ENTA TABLET [Stalevo] | 24 | 265 | New Drug and Strength |
| 16571069301 | CARBIDOPA-LEVODOPA 150 MG-ENTA TABLET [Stalevo] | 24 | 265 | New Drug and Strength |
| 16571069401 | CARBIDOPA-LEVODOPA 200 MG-ENTA TABLET [Stalevo] | 24 | 265 | New Drug and Strength |
| 67877021905 | CEPHALEXIN 500 MG CAPSULE [Keflex] | 40 | 344 | New Manufacturer, Delivery Form and Strength |
| 59390021705 | CIPROFLOXACIN 0.3% EYE DROPS [Ciloxan] | 40 | 344 | New Drug |
| 21922002707 | CLINDAMYCIN PH 1% GEL [ClindaMax] | 26 | 255 | New Manufacturer |
| 69238173208 | CLOBETASOL 0.05% SHAMPOO [Clodan] | 14 | 231 | New Drug and Delivery Form |
| 51672129303 | CLOBETASOL 0.05% SOLUTION [Temovate Scalp] | 29 | 337 | New Drug and Delivery Form |
| 70370510001 | CRENESSITY 100 MG CAPSULE | 0 | 7 | New Drug and Strength |
| 70370505001 | CRENESSITY 50 MG CAPSULE | 0 | 7 | New Drug and Strength |
| 70370525001 | CRENESSITY 50 MG/ML SOLUTION | 0 | 7 | New Drug and Delivery Form |
| 83148002160 | DESOXIMETASONE 0.05% OINTMENT [Topicort LP] | 3 | 42 | New Manufacturer and Delivery Form |
| 70436003604 | DESVENLAFAXINE SUCCNT ER 25 MG TABLET 24H [Pristiq] | 40 | 344 | New Strength |
| 70436001204 | DESVENLAFAXINE SUCCNT ER 50 MG TABLET 24H [Pristiq] | 40 | 344 | New Strength |
| 63323087074 | DEXTROSE 5%-0.9% NACL IV SOLUTION | 40 | 340 | New Manufacturer and Strength |
| 72205003960 | DOFETILIDE 125 MCG CAPSULE [Tikosyn] | 40 | 344 | New Strength |
| 27808023302 | DOXYCYCLINE HYCLATE 100 MG CAPSULE [Vibramycin] | 40 | 342 | New Drug |
| 68180089473 | DROSP-EE-LEVOMEF 3-0.02-0.451 TABLET [Beyaz] | 10 | 97 | New Drug |
| 16714001610 | ENOXAPARIN 40 MG/0.4 ML SYRINGE [Lovenox] | 40 | 344 | New Manufacturer and Strength |
| 49502010202 | EPINEPHRINE 0.3 MG AUTO-INJECTOR [Twinject] | 40 | 342 | New Manufacturer and Strength |
| 81279010420 | ERGOMAR 2 MG TABLET SUBLINGUAL | 1 | 10 | New Drug |
| 69097050731 | ESOMEPRAZOLE DR 2.5 MG SUSPDR PACKET [Nexium] | 0 | 14 | New Strength |
| 69097050831 | ESOMEPRAZOLE DR 5 MG SUSPDR PACKET [Nexium] | 0 | 14 | New Strength |
| 00378336099 | ESTRADIOL 0.0375MG PATCH (1/WK) [Climara] | 39 | 332 | New Strength |
| 00378335199 | ESTRADIOL 0.075 MG PATCH (1/WK) [Climara] | 39 | 332 | New Strength |
| 00378335099 | ESTRADIOL 0.05 MG PATCH (1/WK) [Climara] | 39 | 332 | New Strength |
| 00378336199 | ESTRADIOL 0.06 MG PATCH (1/WK) [Climara] | 39 | 332 | New Strength |
| 00378335299 | ESTRADIOL 0.1 MG PATCH (1/WK) [Climara] | 39 | 330 | New Strength |
| 00378334999 | ESTRADIOL 0.025 MG PATCH (1/WK) [FemPatch] | 39 | 332 | New Drug |
| 70710119308 | ESTRADIOL 0.05 MG PATCH (2/WK) TDSW [Vivelle-Dot] | 38 | 327 | New Manufacturer and Strength |
| 33342030011 | ESZOPICLONE 2 MG TABLET [Lunesta] | 8 | 234 | New Manufacturer and Strength |
| 33342030111 | ESZOPICLONE 3 MG TABLET [Lunesta] | 8 | 232 | New Manufacturer and Strength |
| 50242020201 | EVRYSDI 5 MG TABLET | 1 | 73 | New Delivery Form and Strength |
| 72205002930 | FEBUXOSTAT 80 MG TABLET [Uloric] | 11 | 250 | New Strength |
| 70700030985 | FEIRZA 1.5 MG-30 MCG TABLET [Microgestin Fe 1.5/30] | 36 | 275 | New Drug |
| 70700030785 | FEIRZA 1 MG-20 MCG TABLET [Tarina Fe 1/20] | 36 | 275 | New Drug |
| 27241011703 | FENOFIBRATE 160 MG TABLET [Triglide] | 40 | 344 | New Drug |
| 47781042447 | FENTANYL 25 MCG/HR PATCH TD72 [Duragesic] | 40 | 344 | New Manufacturer and Strength |
| 47781042647 | FENTANYL 50 MCG/HR PATCH TD72 [Duragesic] | 40 | 344 | New Manufacturer and Strength |
| 21922000101 | FLUOCINONIDE 0.05% SOLUTION [Lidex] | 33 | 341 | New Manufacturer and Delivery Form |
| 60505082901 | FLUTICASONE PROP 50 MCG SPRAY [Flonase Childrens Allergy] | 40 | 344 | New Drug |
| 00527258032 | FLUVASTATIN ER 80 MG TABLET 24H [Lescol XL] | 8 | 181 | New Drug |
| 64980028101 | GLIPIZIDE ER 10 MG TABLET 24 [Glucotrol XL] | 40 | 344 | New Strength |
| 64980027903 | GLIPIZIDE ER 2.5 MG TABLET 24 [Glucotrol XL] | 40 | 344 | New Strength |
| 73308043530 | GRISEOFULVIN ULTRA 165 MG TABLET [Fulvicin P/G] | 3 | 65 | New Drug |
| 65162011550 | HYDROCODONE-ACETAMIN 7.5-325 TABLET [Norco] | 40 | 344 | New Manufacturer and Strength |
| 68308074708 | IMVEXXY 4 MCG MAINTENANCE PACK INSERT | 2 | 45 | New Manufacturer and Strength |
| 68308074718 | IMVEXXY 4 MCG STARTER PACK INSR DS PK | 2 | 45 | New Manufacturer and Strength |
| 83257001532 | INSULIN GLARGINE-YFGN U100 INSULN PEN [Semglee] | 3 | 28 | New Delivery Form |
| 81665010210 | ISOSORBIDE MONONIT 10 MG TABLET [Monoket] | 36 | 277 | New Drug and Strength |
| 81665010310 | ISOSORBIDE MONONIT 20 MG TABLET [Monoket] | 36 | 277 | New Drug and Strength |
| 51167054830 | JOURNAVX 50 MG TABLET | 1 | 24 | New Drug |
| 21922002507 | KETOCONAZOLE 2% CREAM (G) [Nizoral] | 40 | 344 | New Manufacturer, Delivery Form and Strength |
| 62332017360 | LACOSAMIDE 150 MG TABLET [Vimpat] | 40 | 344 | New Strength |
| 65162079108 | LIDOCAINE 5% PATCH [Tridacaine] | 40 | 344 | New Manufacturer |
| 62756023290 | LOTEPREDNOL ETABONATE 0.5% EYE DROPS W/DROPPER [Lotemax] | 9 | 178 | New Drug |
| 69784042012 | LOVAZA 1 GM CAPSULE [TRIKLO] | 0 | 1 | New Drug |
| 69238124803 | MEMANTINE-DONEPEZIL ER 14-10MG CAPSULE SPR 24 [Namzaric] | 10 | 147 | New Drug and Strength |
| 62559020730 | MEMANTINE-DONEPEZIL ER 21-10MG CAPSULE SPR 24 [Namzaric] | 10 | 147 | New Drug and Strength |
| 69238124703 | MEMANTINE-DONEPEZIL ER 28-10MG CAPSULE SPR 24 [Namzaric] | 10 | 147 | New Drug and Strength |
| 69292056201 | METOLAZONE 2.5 MG TABLET [Zaroxolyn] | 33 | 342 | New Manufacturer and Strength |
| 69292056401 | METOLAZONE 5 MG TABLET [Zaroxolyn] | 33 | 342 | New Manufacturer and Strength |
| 55111046901 | METOPROLOL SUCC ER 200 MG TABLET 24H [Toprol-XL] | 40 | 344 | New Manufacturer and Strength |
| 66993096045 | METRONIDAZOLE 0.75% CREAM (G) [Vitazol] | 40 | 342 | New Drug |
| 60505132501 | MIDODRINE HCL 10 MG TABLET [ProAmatine] | 40 | 344 | New Manufacturer and Strength |
| 60505132101 | MIDODRINE HCL 5 MG TABLET [ProAmatine] | 40 | 344 | New Manufacturer and Strength |
| 69452034313 | MODAFINIL 200 MG TABLET [Provigil] | 39 | 343 | New Manufacturer and Strength |
| 68462018022 | MUPIROCIN 2% OINTMENT [Centany AT] | 40 | 344 | New Drug |
| 16729008110 | NALTREXONE 50 MG TABLET [ReVia] | 40 | 344 | New Drug |
| 00574416035 | NEOMYC-POLYM-DEXAMET EYE OINTMENT [Poly-Dex] | 40 | 344 | New Manufacturer and Delivery Form |
| 65162032309 | NIACIN ER 1,000 MG TABLET 24H [Niaspan] | 38 | 340 | New Drug |
| 45802024414 | NYSTATIN-TRIAMCINOLONE OINTMENT [Mytrex] | 20 | 192 | New Drug |
| 69238161503 | OFLOXACIN 0.3% EAR DROPS [Floxin] | 40 | 344 | New Manufacturer and Delivery Form |
| 60505056000 | OFLOXACIN 0.3% EYE DROPS [Ocuflox] | 40 | 344 | New Manufacturer and Delivery Form |
| 55111016330 | OLANZAPINE 2.5 MG TABLET [Zyprexa] | 40 | 344 | New Strength |
| 16729032215 | OLMESARTAN MEDOXOMIL 40 MG TABLET [Benicar] | 40 | 338 | New Manufacturer and Strength |
| 43547039109 | OLMESARTAN-HCTZ 20-12.5 MG TABLET [Benicar HCT] | 39 | 339 | New Manufacturer and Strength |
| 68462015713 | ONDANSETRON ODT 4 MG TABLET RAPDIS [Zofran ODT] | 40 | 344 | New Manufacturer and Strength |
| 24478014803 | ONYDA XR 0.1 MG/ML SUSPENSION ER 24H | 0 | 2 | New Drug |
| 42858010401 | OXYCODONE-ACETAMINOPHEN 10-325 TABLET [Percocet] | 40 | 344 | New Manufacturer, Delivery Form and Strength |
| 42858010301 | OXYCODONE-ACETAMINOPHN 7.5-325 TABLET [Percocet] | 40 | 344 | New Manufacturer, Delivery Form and Strength |
| 42858010250 | OXYCODONE-ACETAMINOPHEN 5-325 TABLET [Roxicet] | 40 | 344 | New Manufacturer, Delivery Form and Strength |
| 75826013910 | PHENOBARBITAL 32.4 MG TABLET | 40 | 344 | New Manufacturer and Strength |
| 75826014110 | PHENOBARBITAL 64.8 MG TABLET | 40 | 344 | New Manufacturer and Strength |
| 70069018101 | PILOCARPINE 1% EYE DROPS [Pilocar] | 40 | 344 | New Drug and Strength |
| 70069019101 | PILOCARPINE 2% EYE DROPS [Pilocar] | 40 | 344 | New Drug and Strength |
| 70069020101 | PILOCARPINE 4% EYE DROPS [Pilocar] | 40 | 344 | New Drug and Strength |
| 43068061009 | PONVORY 14-DAY STARTER PACK TABLET DS PK | 0 | 11 | New Drug and Delivery Form |
| 43068062001 | PONVORY 20 MG TABLET | 0 | 11 | New Drug and Delivery Form |
| 64950034516 | PROMETHAZINE-PE 6.25-5 MG/5 ML SYRUP [Prometh VC Plain] | 0 | 13 | New Drug |
| 65162074934 | RIVASTIGMINE 13.3 MG/24HR PATCH [Exelon Patch] | 32 | 340 | New Manufacturer, Delivery Form and Strength |
| 65162082534 | RIVASTIGMINE 4.6 MG/24HR PATCH [Exelon Patch] | 32 | 340 | New Manufacturer, Delivery Form and Strength |
| 65162082634 | RIVASTIGMINE 9.5 MG/24HR PATCH [Exelon Patch] | 32 | 340 | New Manufacturer, Delivery Form and Strength |
| 33342008909 | RIVASTIGMINE 1.5 MG CAPSULE [Exelon] | 40 | 344 | New Manufacturer and Strength |
| 33342009009 | RIVASTIGMINE 3 MG CAPSULE [Exelon] | 40 | 344 | New Manufacturer and Strength |
| 33342009209 | RIVASTIGMINE 6 MG CAPSULE [Exelon] | 40 | 344 | New Manufacturer and Strength |
| 51759050532 | SELARSDI 45 MG/0.5 ML SYRINGE [Yesintek] | 0 | 37 | New Drug and Strength |
| 51759060732 | SELARSDI 90 MG/ML SYRINGE [Yesintek] | 2 | 94 | New Drug and Strength |
| 65862005090 | SIMVASTATIN 5 MG TABLET [Zocor] | 40 | 344 | New Manufacturer and Strength |
| 72606002701 | STEQEYMA 45 MG/0.5 ML SYRINGE | 0 | 1 | New Drug and Strength |
| 72606002801 | STEQEYMA 90 MG/ML SYRINGE | 0 | 2 | New Drug and Strength |
| 43598057530 | TADALAFIL 5 MG TABLET [Cialis] | 40 | 344 | New Strength |
| 24979024407 | TENORMIN 25 MG TABLET | 0 | 3 | New Manufacturer and Strength |
| 69097080232 | TESTOSTERONE CYP 200 MG/ML VIAL [Virilon] | 40 | 338 | New Manufacturer |
| 70726030301 | TIGLUTIK 50 MG/10 ML ORAL SUSPENSION | 0 | 22 | New Drug |
| 42571013027 | TRAVOPROST 0.004% EYE DROPS [Travatan Z] | 29 | 282 | New Drug |
| 42571038519 | TRIAMCINOLONE 0.1% LOTION [Kenalog] | 40 | 343 | New Manufacturer and Strength |
| 43547031509 | VALSARTAN-HCTZ 320-25 MG TABLET [Diovan HCT] | 40 | 343 | New Manufacturer and Strength |
| 62332023330 | VILAZODONE HCL 20 MG TABLET [VIIBRYD] | 40 | 344 | New Strength |
| 50632001602 | VIVOTIF COATED ORAL CAPSULE 4-PACK BLISTER PACK | 37 | 319 | New Drug |
| 70700031085 | XARAH FE 1 MG/20-30-35 MCG TABLET [Xarah Fe] | 34 | 228 | New Drug |
| 65862015901 | ZOLPIDEM TARTRATE 5 MG TABLET [Ambien] | 40 | 344 | New Strength |
- Ask your prescriber about trying the generic.
- Check for an alternative formulary drug.
- Ask your plan to cover a non-formulary drug.
You will need to work with your doctor or prescriber to explain why you are not able to use the generic medication or why no other formulary drug is acceptable. If your formulary exception is denied, you have the right to appeal your plan’s decision.
- Consider using a Special Enrollment Period and move to another Medicare plan that provides coverage of all your prescription and health needs.
Our online Formulary Browser and Drug Finder
You can review any Medicare plan formulary using the on this site Formulary Browser found at: FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your Service Area using our Drug Finder found at on this site.