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March-April 2026 Medicare Drug List Updates: Sixty-seven (67) medications added to the 2026 Medicare Part D Drug plan formularies.

Monthly Formulary changes · published Apr 28, 2026

The March-April 2026 Medicare Part D prescription drug plan formulary (drug list) data is now online and included in our Formulary Browser and the drug finder Drug Finder.

The March-April formulary updates include the addition of 101 new National Drug Codes (NDCs), representing 67 different prescription drugs, many with multiple strengths.

The formulary updates impact both stand-alone Medicare Part D plans (PDPs) and Medicare Advantage plans with drug coverage (MAPDs).


Highlights of the March-April 2026 Formulary updates eight (8) newly-introduced brand-name drugs

The March-April drug data updates include twenty-six (26) new brand-name drugs, eight (8) of which are newly introduced brand-name drugs, some with multiple strengths. These drugs include:
  • BREKIYA®,
  • ENBUMYST®,
  • ENSACOVE®,
  • FORZINITY®,
  • RHAPSIDO®,
  • SELARSDI®,
  • ZOLOFT SOLUTION®, and
  • ZYPREXA INTRAMUSCULAR®.

The March-April 2026 Formulary updates include ten (10) newly-added generic drugs

The March-April Medicare Part D drug data also includes fourty-one (41) new generic medications, ten (10) of which are newly-introduced generic drugs. These drugs include:
  • BUTALB-ACETAMIN-CAFF [Zebutal®],
  • CDV ADALIMU-BWWD(CF) [HADLIMA®],
  • CRYSELLE [Turqoz®],
  • DALBAVANCIN HCL [DALVANCE®],
  • DICHLORPHENAMIDE [Keveyis®],
  • JAYTHARI [Pyquvi®],
  • LIOMNY,
  • MECLIZINE [Travel-Ease®],
  • PREDNISONE [RAYOS®], and
  • RANITIDINE [Zantac Maximum Strength®].
Please note that these new generic and brand-name drugs are not available on all Medicare Part D or Medicare Advantage drug plans - and you can review the chart to see the (often limited) number of plan formularies that now include these drugs.


Reminders about Medicare prescription drug plan formulary changes
  1. Medicare Part D plans (PDPs and MAPDs) can change their formulary or drug list during the year and may drop one of your formulary medication mid-year for specific Medicare-allowable reasons (such as a new generic drug is available), but there are steps you can take if your medication is no longer covered by your prescription drug plan.

  2. In most cases, your Medicare Part D plan will notify you if the plan drops a medication you are currently using.

Good to know: What is the NDC?

The NDC or National Drug Code is used to uniquely identify a particular drug, manufacturer, strength, and packaging combination. The NDC is often shown on your prescription bottle as an 11-digit code (see the charts below) or could be formatted as 00000-0000-00 where the first set of numbers identifies the drug manufacturer, the second set of number identifies the product and strength, and the third set of numbers identifies the packaging.  You can read more on this site


Summary of March-April 2026 NDC changes

There are many reasons for NDCs to be added to the Medicare Part D program, a summary for all 101 new March-April 2026 NDCs is as follows:

Reason for NDC Addition Occurrences
New Delivery Form 1
New Delivery Form and Strength 3
New Drug 21
New Drug and Strength 33
New Manufacturer 2
New Manufacturer and Delivery Form 2
New Manufacturer and Strength 18
New Manufacturer, Delivery Form and Strength 3
New Packaging 2
New Strength 16
Grand Total 101

The following chart details the 101 new manufacturer / drug-strength / packaging combinations (NDCs) that were added to one or more Medicare Part D formularies in the most recent updates -- as you will notices, some drugs are only covered by a few Medicare plans.

You can click on the Drug Name below to go to our on this site Drug Finder ( on this site) and see the details of how this drug is covered by all Medicare Part D plans (PDPs) in Florida (our example state).  You can then change the state in our search form for details of drug coverage in your service area.
NDC Drug Name Number of
PDP Formularies*
Number of
MAPD Formularies*
Notes
51759036117ADALIMUMAB-RYVK(CF) AI 80 MG AUTOINJECTOR KIT [Yuflyma]03New Manufacturer, Delivery Form and Strength
42794000308ADEFOVIR DIPIVOXIL 10 MG TABLET [Hepsera]31297New Drug
10135069201AMANTADINE 100 MG TABLET [Symmetrel]12209New Manufacturer and Delivery Form
75907000530AMIODARONE HCL 100 MG TABLET [Pacerone]33287New Manufacturer and Strength
00480331865AMPHETAMINE ER 12.5 MG ODT TABLET RAP BP [Adzenys XR]020New Drug and Strength
00480331965AMPHETAMINE ER 15.7 MG ODT TABLET RAP BP [Adzenys XR]020New Drug and Strength
00480332065AMPHETAMINE ER 18.8 MG ODT TABLET RAP BP [Adzenys XR]020New Drug and Strength
00480331565AMPHETAMINE ER 3.1 MG ODT TABLET RAP BP [Adzenys XR]020New Drug and Strength
00480331665AMPHETAMINE ER 6.3 MG ODT TABLET RAP BP [Adzenys XR]020New Drug and Strength
00480331765AMPHETAMINE ER 9.4 MG ODT TABLET RAP BP [Adzenys XR]020New Drug and Strength
63459070060AMRIX ER 15 MG CAPSULE 24H01New Drug and Strength
63459070160AMRIX ER 30 MG CAPSULE 24H01New Drug and Strength
00713094230BENICAR 40 MG TABLET01New Strength
64896050902BREKIYA 1 MG/ML AUTOINJECTOR01New Drug
81279012360BUCAPSOL 10 MG CAPSULE02New Strength
24979024806BUPROPION HCL XL 450 MG TABLET ER 24H [Forfivo XL]242New Drug
13107007501BUTALB-ACETAMIN-CAFF 50-325-40 CAPSULE [Zebutal]278New Drug
83457018601CDV ADALIMU-BWWD(CF) 40MG/0.4ML SYRINGE [HADLIMA]653New Drug and Strength
83457018701CDV ADALIMU-BWWD(CF) AI 40 MG AUTO INJECTOR [HADLIMA]653New Drug and Strength
00480349316CRYSELLE-28 TABLET [Turqoz]34282New Drug
00115143713CYCLOBENZAPRINE ER 30 MG CAPSULE 24H [Amrix]01New Manufacturer and Strength
71288003450DALBAVANCIN HCL 500 MG VIAL [DALVANCE]19New Drug
16571024201DICHLORPHENAMIDE 50 MG TABLET [Keveyis]028New Drug
62135062560DOXYCYCLINE 50 MG TABLET [TARGADOX]120New Drug
31722016860DULOXETINE HCL DR 20 MG CAPSULE DR [Drizalma]35297New Manufacturer and Strength
58151012793EFFEXOR XR 150 MG CAPSULE ER 24H01New Strength
23155070401ENALAPRIL MALEATE 2.5 MG TABLET [Vasotec]35297New Strength
84388000512ENBUMYST 0.5 MG SPRAY028New Drug
83076110006ENSACOVE 100 MG CAPSULE35297New Drug and Strength
83076102503ENSACOVE 25 MG CAPSULE35297New Drug and Strength
68180073973ENSKYCE 28 TABLET [Solia]33267New Drug
73159000460ERTACZO 2% CREAM (G)14New Drug
68382044206ESOMEPRAZOLE MAG DR 40 MG CAPSULE DR [Nexium]21290New Manufacturer and Delivery Form
16714078101EZETIMIBE-SIMVASTATIN 10-80 MG TABLET [Vytorin]24279New Manufacturer and Strength
64980070501FEXMID 7.5 MG TABLET01New Drug
71776010005FLAREX 0.1% EYE DROPS EYE DROPPER240New Drug
72507080004FORZINITY 280 MG/3.5 ML VIAL05New Drug
70710213103JAYTHARI 22.75 MG/ML ORAL SUSPENSION [Pyquvi]08New Drug
10122043028JUXTAPID 30 MG CAPSULE041New Manufacturer and Strength
00310063560KOSELUGO 5 MG SPRINKLE CAPSULE35297New Delivery Form and Strength
00310064060KOSELUGO 7.5 MG SPRINKLE CAPSULE35297New Delivery Form and Strength
68001038200LABETALOL HCL 200 MG TABLET [Trandate]35297New Manufacturer and Strength
58657060401LABETALOL HCL 300 MG TABLET [Trandate]35297New Manufacturer and Strength
42794013212LIOMNY 25 MCG TABLET33260New Drug and Strength
42794013112LIOMNY 5 MCG TABLET33260New Drug and Strength
42794013312LIOMNY 50 MCG TABLET33260New Drug and Strength
61958330102LIVDELZI 10 MG CAPSULE037New Drug
58151023977LYRICA 100 MG CAPSULE01New Strength
58151024177LYRICA 200 MG CAPSULE01New Strength
58151024377LYRICA 225 MG CAPSULE01New Strength
58151023877LYRICA 75 MG CAPSULE01New Strength
65162044110MECLIZINE 12.5 MG TABLET [Antivert]35290New Drug and Strength
62135095460MECLIZINE 50 MG TABLET [Antivert]29New Drug and Strength
65162044210MECLIZINE 25 MG TABLET [Travel-Ease]35294New Drug and Strength
68382091818METHYLPREDNISOLONE 16 MG TABLET [Medrol Dosepak]35297New Drug and Strength
00603459315METHYLPREDNISOLONE 4 MG DOSE PACK TABLET [Medrol Dosepak]35297New Drug and Strength
42806040001METHYLPREDNISOLONE 4 MG TABLET [Medrol Dosepak]35297New Drug and Strength
68382091911METHYLPREDNISOLONE 32 MG TABLET [Medrol]35297New Drug and Strength
68382091711METHYLPREDNISOLONE 8 MG TABLET [Medrol]35297New Drug and Strength
57237010299METOPROLOL TARTRATE 100 MG TABLET [Lopressor]35297New Drug and Strength
57237010199METOPROLOL TARTRATE 50 MG TABLET [Lopressor]35297New Drug and Strength
59651058901NADOLOL 20 MG TABLET [Corgard]19235New Drug and Strength
59651025101NADOLOL 40 MG TABLET [Corgard]19235New Drug and Strength
59651025201NADOLOL 80 MG TABLET [Corgard]19235New Drug and Strength
24208079535NEOMYC-POLYM-DEXAMET EYE OINTMENT [Poly-Dex]35297New Delivery Form
58151028101NEURONTIN 100 MG CAPSULE01New Manufacturer and Strength
58151028301NEURONTIN 400 MG CAPSULE01New Manufacturer and Strength
58151028401NEURONTIN 600 MG TABLET01New Manufacturer, Delivery Form and Strength
58151028501NEURONTIN 800 MG TABLET01New Manufacturer, Delivery Form and Strength
60505484903NUVIGIL 200 MG TABLET01New Manufacturer and Strength
60505485003NUVIGIL 250 MG TABLET01New Manufacturer and Strength
60505484603NUVIGIL 50 MG TABLET01New Manufacturer and Strength
00002311611OMVOH 200 MG/2 ML PEN INJECTOR01New Manufacturer and Strength
00002144211OMVOH 200 MG/2 ML SYRINGE01New Manufacturer and Strength
16571067101PHENOBARBITAL 16.2 MG TABLET35297New Manufacturer and Strength
16571066801PHENOBARBITAL 97.2 MG TABLET35297New Manufacturer and Strength
43547055350POTASSIUM CL ER 10 MEQ CAPSULE ER [Micro-K Extencaps]34294New Manufacturer and Strength
43598088630PREDNISONE DR 1 MG TABLET [RAYOS]27New Drug and Strength
43598088730PREDNISONE DR 2 MG TABLET [RAYOS]27New Drug and Strength
64380078408PREDNISONE 10 MG TABLET [Sterapred DS]35297New Drug and Strength
59676057830PREZCOBIX 675 MG-150 MG TABLET35297New Strength
60505485103PROVIGIL 100 MG TABLET01New Manufacturer and Strength
64980063603RANITIDINE 150 MG TABLET [Zantac Maximum Strength]03New Drug and Strength
64980063703RANITIDINE 300 MG TABLET [Zantac]03New Drug and Strength
00078148320RHAPSIDO 25 MG TABLET04New Drug
51759050513SELARSDI 45 MG/0.5 ML VIAL0100New Drug
69102041801SUBVENITE 10 MG/ML ORAL SUSPENSION34281New Delivery Form and Strength
00548231100TERIPARATIDE 560MCG/2.24ML PEN INJECTOR [FORTEO]24279New Drug
72888000801TRAMADOL HCL 100 MG TABLET123New Strength
66302063003TYVASO DPI 32-64 MCG MAINTENANCE KIT CART INHAL017New Packaging
66302064003TYVASO DPI 48-64 MCG MAINTENANCE KIT CART INHAL017New Packaging
66302068003TYVASO DPI 80 MCG CARTRIDGE INHAL017New Strength
65219086201USTEKINUMAB-AAUZ 45 MG SYRINGE [Yesintek]051New Manufacturer
65219086626USTEKINUMAB-AAUZ 90 MG/ML SYRINGE [Yesintek]051New Manufacturer
23155085878VANCOMYCIN HCL 125 MG CAPSULE [Vancocin]35297New Strength
00480400062VESTURA 3 MG-0.02 MG TABLET [Yaz]34219New Drug
58151057693ZOLOFT 100 MG TABLET01New Strength
58151057593ZOLOFT 50 MG TABLET01New Strength
58151060135ZOLOFT 20 MG/ML ORAL CONC [Zoloft Solution]01New Strength
80610010560ZORYVE 0.05% CREAM (G)25New Strength
61269064020ZYPREXA 10 MG VIAL [Zyprexa Intramuscular]35New Drug
If your brand-name drug is no longer covered by your Medicare Part D plan, you can use the 30-day notice period (if notice is provided) to:
Learn more in our article: How a mid-year formulary change can affect your Medicare Part D drug coverage.

Our online Formulary Browser and Drug Finder

You can review any Medicare plan formulary using the on this site Formulary Browser found at: FormularyBrowser.com or compare how any medication is covered on all Medicare plans in your Service Area using our Drug Finder found at on this site.